Biocare’sPromARK™seriesintroducesMouse-on-CanineHRP-PolymerDetection.Thisdetectionisspeciallydesignedforusingmouseantibodiesoncanineandfelinetissuesandutilizesbiotin-freehorserADIshperoxidase(HRP)polymertechnology.Theadvantagesofthispolymertechnologyareincreasedsensitivity,reductionofIHCsteps(noAvidin/BiotinblockorLink/Probe),andminimalcross-reactivitytoendogenouscanineandfelineIgG.TheMouse-on-Caninedetectioncanbeusedwithparaffin-embeddedtissuesandcanbeperformedmanuallyoronautomatedstainingplatforms.TheadditionofproprietaryblockerstothedetectionreagentpermitstheuseofanyofBiocareMedical’sretrievalsolutions(Reveal/Borg/Diva)orenzymeswiththeeliminationofendogenousIgGornon-specificbackgroundstaining.TemperaturedependentprotocolscanbeconvenientlyperformedusingBiocare’sDecloakingChamber.TheMouse-on-CanineHRP-PolymermaybecombinedwiththeRabbit-on-CanineHRP-PolymertocreateauniversalpolymerdetectionthatwilllabelbothmouseandrabbitantibodieswithHRP.RefertoTechnicalNote#4foradditionalinformation.TheMouse-on-CanineHRP-PolymermaybecombinedwiththeRabbit-on-CanineHRP-PolymertocreateauniversalpolymerdetectionthatwilllabelbothmouseandrabbitantibodieswithHRP.RefertoTechnicalNote#4foradditionalinformation.